 
Tony Stark was born a woman (Natasha Stark) rather than a man; Stark's superhero alter-ego in this universe is Natasha Stark/Iron Woman. In this universe, the Civil War (from Marvel) has been averted wholly because Natasha and Steve Rogers were romantically involved, and eventually married. Their universe was one of the many Reed Richards came across while searching for alternate realities where the Civil War had ended differently, Richards stated that the two were "a deterrent to each others' more aggressive behavior," which "allowed this Earth's Reed Richards to successfully complete the Superhero Registration Program and begin the Fifty State Initiative."